NYU Langone experts present at annual meeting of Radiological Society of North America

Public release date: 28-Nov-2011
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Contact: Craig Andrews
craig.andrews@nyumc.org
212-404-3511
NYU Langone Medical Center / New York University School of Medicine

Experts from the Department of Radiology at NYU Langone Medical Center will present new research and advanced imaging techniques at the 97th Scientific Assembly and Annual Meeting of the Radiology Society of North America (RSNA) in Chicago, November 27 - December 2, 2011. Experts are available to comment on their research as well as the latest technology and its application for specific conditions. Presentations include:

*Genitourinary: Evaluating Renal Function*

Monday, November 28 at 3:00 PM
Hersh Chandarana, MD, assistant professor, Department of Radiology, Division of Abdominal Imaging (Moderator)
This scientific session will focus on imaging techniques and tools being investigated for the evaluation of renal function.

*Are Screening Radiographs Necessary to Detect Incomplete Atypical Femoral Fractures in Asymptomatic Patients on Long-term Bisphosphonate Therapy?*

Tuesday, November 29 at 11:10 AM
Zehava Rosenberg MD, professor, Department of Radiology, Division of Musculoskeletal Radiology, and Department of Orthopaedic Surgery
Valerie H. Peck, MD, clinical associate professor, Department of Medicine, Division of Endocrinology
This presentation will highlight research into the frequency and imaging features of incomplete atypical femoral fractures in asymptomatic patients on long-term bisphosphonate therapy.

*Outcomes of Breast MRI in Women at Intermediate Risk and High Risk for Breast MRI: A Retrospective Review at a Single Institution*

Tuesday, November 29 at 3:10 PM
Amy Melsaether, MD, assistant professor, Department of Radiology, Division of Breast Imaging
Cecilia Mercado, MD, assistant professor, Department of Radiology, Division of Breast Imaging
Linda Moy, MD, assistant professor, Department of Radiology, Division of Breast Imaging
This presentation will discuss the impact of breast MRI as a tool to monitor women classified as intermediate or high risk for breast cancer.

*Improved Efficiency of Computed Tomography Interpretation Utilizing an Automated Lung Nodule Matching Program*

Wednesday, November 30 at 11:40 AM
Jane Ko, MD, associate professor, Department of Radiology, Division of Chest Radiology
Francis Girvin, MD, assistant professor; Departments of Radiology, Division of Chest Radiology
Maj Wickstrom, MD, assistant professor; Department of Radiology, Division of Chest Radiology
John Fantauzzi, MD, assistant professor; Department of Radiology, Division of Chest Radiology
David Naidich, MD, professor, Department of Radiology, Division of Chest Radiology, and Medicine
This presentation will review results of a study evaluating the use of an automated lung nodule matching program to significantly improve a radiologist's diagnostic efficiency by increasing the speed of CT exam interpretation, ultimately decreasing report turnaround time.

###

The Department of Radiology at NYU Langone Medical Center is a leader in advanced diagnostic imaging and had an extensive research program ranked among the top nationwide in NIH funding. The department has more than 100 American Board of Radiology accredited radiologists practicing across 12 subspecialties, including neuroradiology and nuclear medicine as well as abdominal, biomedical, breast, cardiac, thoracic and musculoskeletal imaging. The facility is accredited by the American College of Radiology (ACR) and the faculty is well-known for integrating the latest radiographic technology with the work of the basic scientists and clinical researchers across the Medical Center, as well as advancing low-dose scanning initiatives. For more information go to http://radiology.med.nyu.edu/.

About NYU Langone Medical Center

NYU Langone Medical Center, a world-class, patient-centered, integrated, academic medical center, is one on the nation's premier centers for excellence in clinical care, biomedical research and medical education. Located in the heart of Manhattan, NYU Langone is composed of three hospitals Tisch Hospital, its flagship acute care facility; the Rusk Institute of Rehabilitation Medicine, the world's first university-affiliated facility devoted entirely to rehabilitation medicine; and the Hospital for Joint Diseases, one of only five hospitals in the nation dedicated to orthopaedics and rheumatology plus the NYU School of Medicine, which since 1841 has trained thousands of physicians and scientists who have helped to shape the course of medical history. The medical center's tri-fold mission to serve, teach and discover is achieved 365 days a year through the seamless integration of a culture devoted to excellence in patient care, education and research. For more information, go to www.NYULMC.org.

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 28-Nov-2011
[ | E-mail | Share ]

Contact: Craig Andrews
craig.andrews@nyumc.org
212-404-3511
NYU Langone Medical Center / New York University School of Medicine

Experts from the Department of Radiology at NYU Langone Medical Center will present new research and advanced imaging techniques at the 97th Scientific Assembly and Annual Meeting of the Radiology Society of North America (RSNA) in Chicago, November 27 - December 2, 2011. Experts are available to comment on their research as well as the latest technology and its application for specific conditions. Presentations include:

*Genitourinary: Evaluating Renal Function*

Monday, November 28 at 3:00 PM
Hersh Chandarana, MD, assistant professor, Department of Radiology, Division of Abdominal Imaging (Moderator)
This scientific session will focus on imaging techniques and tools being investigated for the evaluation of renal function.

*Are Screening Radiographs Necessary to Detect Incomplete Atypical Femoral Fractures in Asymptomatic Patients on Long-term Bisphosphonate Therapy?*

Tuesday, November 29 at 11:10 AM
Zehava Rosenberg MD, professor, Department of Radiology, Division of Musculoskeletal Radiology, and Department of Orthopaedic Surgery
Valerie H. Peck, MD, clinical associate professor, Department of Medicine, Division of Endocrinology
This presentation will highlight research into the frequency and imaging features of incomplete atypical femoral fractures in asymptomatic patients on long-term bisphosphonate therapy.

*Outcomes of Breast MRI in Women at Intermediate Risk and High Risk for Breast MRI: A Retrospective Review at a Single Institution*

Tuesday, November 29 at 3:10 PM
Amy Melsaether, MD, assistant professor, Department of Radiology, Division of Breast Imaging
Cecilia Mercado, MD, assistant professor, Department of Radiology, Division of Breast Imaging
Linda Moy, MD, assistant professor, Department of Radiology, Division of Breast Imaging
This presentation will discuss the impact of breast MRI as a tool to monitor women classified as intermediate or high risk for breast cancer.

*Improved Efficiency of Computed Tomography Interpretation Utilizing an Automated Lung Nodule Matching Program*

Wednesday, November 30 at 11:40 AM
Jane Ko, MD, associate professor, Department of Radiology, Division of Chest Radiology
Francis Girvin, MD, assistant professor; Departments of Radiology, Division of Chest Radiology
Maj Wickstrom, MD, assistant professor; Department of Radiology, Division of Chest Radiology
John Fantauzzi, MD, assistant professor; Department of Radiology, Division of Chest Radiology
David Naidich, MD, professor, Department of Radiology, Division of Chest Radiology, and Medicine
This presentation will review results of a study evaluating the use of an automated lung nodule matching program to significantly improve a radiologist's diagnostic efficiency by increasing the speed of CT exam interpretation, ultimately decreasing report turnaround time.

###

The Department of Radiology at NYU Langone Medical Center is a leader in advanced diagnostic imaging and had an extensive research program ranked among the top nationwide in NIH funding. The department has more than 100 American Board of Radiology accredited radiologists practicing across 12 subspecialties, including neuroradiology and nuclear medicine as well as abdominal, biomedical, breast, cardiac, thoracic and musculoskeletal imaging. The facility is accredited by the American College of Radiology (ACR) and the faculty is well-known for integrating the latest radiographic technology with the work of the basic scientists and clinical researchers across the Medical Center, as well as advancing low-dose scanning initiatives. For more information go to http://radiology.med.nyu.edu/.

About NYU Langone Medical Center

NYU Langone Medical Center, a world-class, patient-centered, integrated, academic medical center, is one on the nation's premier centers for excellence in clinical care, biomedical research and medical education. Located in the heart of Manhattan, NYU Langone is composed of three hospitals Tisch Hospital, its flagship acute care facility; the Rusk Institute of Rehabilitation Medicine, the world's first university-affiliated facility devoted entirely to rehabilitation medicine; and the Hospital for Joint Diseases, one of only five hospitals in the nation dedicated to orthopaedics and rheumatology plus the NYU School of Medicine, which since 1841 has trained thousands of physicians and scientists who have helped to shape the course of medical history. The medical center's tri-fold mission to serve, teach and discover is achieved 365 days a year through the seamless integration of a culture devoted to excellence in patient care, education and research. For more information, go to www.NYULMC.org.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2011-11/nlmc-nle112811.php

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Primal Wisdom: Study Indicates Prostate Cancer Is Reversible By Diet

According to the National Cancer Institute, each year in the U.S., 240,890 men get diagnosed with prostate cancer, and 33,720 men die from it.

According to the American Cancer Society,

"About 1 man in 6 will be diagnosed with prostate cancer during his lifetime. More than 2 million men in the United States who have been diagnosed with prostate cancer at some point are still alive today.

"Prostate cancer is the second leading cause of cancer death in American men, behind only lung cancer. About 1 man in 36 will die of prostate cancer."

I have a family history of prostate cancer, so I have a personal interest in prevention and remedy for this disease of civilization.

According to some people, whole grains and legumes cause or promote the diseases of civilization, including cancer.

If this disease is caused by eating grains and legumes, then any diet based on grains and legumes should promote cancer.? If you give men living with prostate cancer a diet rich in whole grains and legumes, you should see a promotion of the cancer.

My friend, Gordon Saxe, M.P.H., Ph.D., M.D., professor of medicine at U.C.S.D.,? has actually tested this hypothesis, albeit unintentionally.

Gordon has lead pilot research in which men with diagnosed with prostate cancer were taught to eat a diet consisting of whole grains, legumes, vegetables, fruits, nuts, and seeds, while eliminating animal? products, based on evidence [discussed here] that this dietary pattern may reduce the risk or progression of prostate cancer.

If whole grains and legumes promote prostate cancer then these men should have had an accelerated progression of their cancers.? However, in the first study, over six months, this intervention produced just the opposite effect:? a 100-fold reduction in the rate of rise of their disease, as measured by the rate of change in levels of prostate-specific antigen (PSA).? As stated by Saxe et al:

"The rate of PSA increase decreased in 8 of 10 men, while 3 had a decrease in absolute PSA. Results of the signed rank test indicated a significant decrease in the rate of increase in the intervention period (p = 0.01). Estimated median doubling time increased from 6.5 months (95% confidence interval 3.7 to 10.1) before to 17.7 months (95% confidence interval 7.8 to infinity) after the intervention. Nine of 10 participants in the study had reduction in the rate of rise of their PSA, a marker for progression of disease."

When 9 of 10 people respond in the very same way to an intervention, in this case with a reduction in rate of rise of PSA, this tends to suggest that the effect is no accident and most likely indicates a definite therapeutic effect of the intervention.

In the second study, involving 14 men, Saxe et al produced a similar result.? In this second study they explored the biological mechanisms involved:

"During the first 3 months of the intervention, as both median WHR and body weight declined significantly, the median rate of PSA rise not only declined but became negative, reflecting a slight reduction in absolute PSA and possibly disease regression in patients with absolute reductions. Conversely, during the second 3 months of the intervention, when median body weight increased (though not significantly), median PSA began to rise again, albeit more slowly than during the period prior to Baseline."

This second study suggested that weight-related metabolic changes may have mediated the reduction in rate of PSA increase.? In other words, the intervention resulted in a loss of body fat and concommitant metabolic changes related to reduction of body fatness, including an increase in sex hormone binding globulin, that influence prostate cancer.

"Assuming that the attenuation of PC progression was mediated by weight-related metabolic changes, a question arises as to what aspect of intervention brought about the observed reduction in adiposity. Earlier ⁵³, we described large increases during months 0?3 in intake of whole grains and vegetables, food groups which are fiber and water-rich, very low in fat, and therefore of low energy density. However, intake of these foods declined slightly during months 3?6. Weight loss during the first three months may possibly have resulted from replacing energy-rich foods with energy-poor foods, and the slight increase in body weight during the second three months may have resulted from a small degree of dietary recidivism."?

So this intervention, based on increasing intake of whole grains, legumes, etc., resulted in body fat reduction during the period when the subjects ate the most of these foods, and body weight increased during the period when these subjects ate less of these foods.? This clearly undermines the idea that diets rich in grains and legumes cause two of the major diseases of civilization, i.e. obesity and cancer.

Saxe et al consider the possibility that any diet that induces weight loss may reduce cancer progression.

"A second question that naturally arises regarding the reduction in adiposity is whether it matters, in terms of effects on prostate cancer progression, how it is achieved. One aspect of this question has to do with the preferred dietary strategy for reducing energy intake. Another facet regards whether it is more desirable to increase energy expenditure or decrease intake to achieve this end. Although our study and its findings did not address these issues, they remain important ones that warrant consideration in the planning and design of future behavioral approaches to the management of progressive PC. What can be said is that while both a plant-based diet and a high-protein, low-carbohydrate diet high in foods of animal origin (such as the popular Atkins diet) may both result in weight loss, the former is far more consistent with the dietary cancer prevention guidelines of various agencies (69).⁵⁴ "

Some people reject those cancer prevention guidelines of various agencies, which emphasize increased consumption of whole plant foods and decreased consumption of animal products, claiming that whole grains and legumes are the true causes of diseases of civilization.?? These two studies, among others, weaken that claim.?

So far, the only studies I can find testing the effect of a low-carbohydrate diet on prostate cancer were done with mice, not men.? In this one, researchers from Duke Prostate Center fed mice with prostate cancer either a "Western" diet,? "low-fat high-carbohydrate" diet, or a zero-carbohydrate diet.? The results:

"Fifty-one days after injection [with xenograft tumors], NCKD mice tumor volumes were 33% smaller than Western mice (rank-sum, P = 0.009). There were no differences in tumor volume between low-fat and NCKD mice. Dietary treatment was significantly associated with survival (log-rank, P = 0.006), with the longest survival among the NCKD mice, followed by the low-fat mice."

I don't have access to the full text, but if done in a typical fashion, all diets would have been pellets made from isolated nutrients (e.g. casein, starch, sugar, etc.) so this can't tell us much about what would happen in humans if we compared a whole foods vegan diet (whole grains, legumes, vegetables, fruits, nuts, seeds) to a zero-carbohydrate diet (meat and fat only).? The effects of a casein-based zero-carbohydrate diet on mice might be very different from the effects of a meat-based zero-carbohydrate diet on humans.

In a second study, Masko et al fed mice diets containing 0, 10, or 20 percent carbohydrate and again injected them with prostate cancer cells.? As a 'control' they fed a group of mice a 12% fat diet, but they did not inject cancer cells into these mice--which to me means they weren't much of a control group, because they differed from the others not only in dietary composition but also in absence of tumor injection.

The full text of this study tells us the components of all diets:? corn oil, lard, milk fat, casein, dl-methionine, dextrine, maltodextrine, corn starch, sucrose, and isolated vitamins and minerals.?

In the low-fat arm, 72% of calories came from carbohydrate, and 50% of total calories came from sucrose, which means that about 25% of total calories came from refined fructose.? Meanwhile, in the 10% and 20% carbohydrate arms, all of the carbohydrate was provided in the form of corn starch.?

This makes me wonder again about diet composition in the other Duke University study cited above.? Were those mice on the low fat diet also eating a 50% sucrose/25% fructose diet?? If so, did this rig the study, intentionally or not, so that the low fat group would have more body fat and shorter lifespan than the zero-carbohydrate group??

Moving on, all the mice got all of their protein from casein-plus-methionine, none ate any meat.? Most people eating low carbohydrate diets eat cooked meats, not isolated casein, as their main protein source.? Meat is nutritionally complex, and affected by cooking process, in ways that may result in it having a different effect on prostate cancer than casein-plus-methionine.? For example, unlike the casein-methionine mix fed to these mice, meat contains heme iron and if cooked at high heat, heterocyclic amines, all of which have been linked to prostate cancer causation or promotion [e.g. Sinha et al full text].? So it is not clear how a study of mice eating a low carbohydrate diet wherein casein is the main protein will apply to people eating low carbohydrate diets wherein cooked meat, poultry, and fish are the main protein sources.

Masko et al found that the survival rates of the mice in the 0, 10, and 20 percent carbohydrate groups were similar.? They liked this finding because, as they say, people find it extremely difficult to follow zero-carbohdyrate diets, so now they are ready to test the 20 percent carbohydrate diet on human prostate cancer patients.?

Masko et al also found that the mice in the 20% carbohydrate group had the lowest insulin level, about which they comment:

"It was unexpected that the lowest levels of insulin were observed in mice fed with 20% carbohydrate, but there are possible explanations for this phenomenon. First, there is always the possibility for a type I error in the analysis. Second, it is known that low-carbohydrate diets promote insulin sensitivity in animals (38) and humans (39, 40). Thus, it is possible that a diet containing a small amount of carbohydrates may actually improve insulin sensitivity compared with a diet completely lacking of carbohydrates."

Perhaps unknown to Masko et al, it is also 'possible' that a diet containing an even large amount of carbohydrate may actually improve insulin sensitivity compared to a diet with only 20% carbohydrate. In 1971, Brunzell et al [abstract only] evaluated the effect of increased dietary carbohydrate at the expense of fat in humans, both non-diabetic and mildly diabetic.? In the New England Journal of Medicine they reported that after feeding these subjects a diet providing 85 percent of energy as carbohydrate for 10 days,

"Fasting plasma glucose levels fell in all subjects and oral glucose tolerance (0 to 120-minute area) significantly improved ..... Fasting insulin levels also were lower on the high carbohydrate diet; however, insulin responses to oral glucose did not significantly change. These data suggest that the high carbohydrate diet increased the sensitivity of peripheral tissues to insulin."

?An diet supplying 85 percent of energy as carbohydrate is by necessity very low in fat, so perhaps Brunzell et al could have emphasized that this very low fat diet increased insulin sensitivity.? The mice of Masko et al that got the 20 percent carbohydrate diet had a lower fat intake than the mice on the zero-carbohydrate diet; rather than increasing carbohydrate being responsible for promoting insulin sensitivity, perhaps it is reducing fat (replacing it with starch) that does the trick.?

Anyway, the Masko et al study has a few features that make me skeptical that they will have similar results in humans.? I feel curious to see if their approach will have results as good as those found by Saxe et al.

Source: http://donmatesz.blogspot.com/2011/11/study-indicates-prostate-cancer-is.html

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Philippines say arrested hackers funded by Saudi group (Reuters)

MANILA/BOSTON (Reuters) ? Philippine police and the FBI have arrested four people that Manila said were paid by a militant Saudi Arabian-based group to hack into U.S. telecom AT&T's system, but the company said it was neither targeted nor breached.

The Philippines' Criminal Investigation and Detection Group (CIDG) said those arrested in Wednesday's operation in Manila with the Federal Bureau of Investigation were paid by the same group the FBI said had funded the November 2008 attacks in Mumbai.

"The hacking activity resulted in almost $2 million in losses incurred by the company," the CIDG said in a statement.

It did not name the group who it said had funded the Mumbai attacks, but India has blamed the militant Pakistan-based Lashkar-e-Taiba (LeT) for carrying out the attacks which killed 166 people.

AT&T, the No. 2 U.S. mobile provider, said it "ended up writing off some fraudulent charges that appeared on customer bills" but did not comment on the $2 million figure.

"AT&T and its network were neither targeted nor breached by the hackers," AT&T spokeswoman Jan Rasmussen said. "AT&T only assisted law enforcement in the investigation that led to the arrest of a group of hackers."

Police said the suspects had hacked into the trunk-lines of different telecom companies, including AT&T, with revenues diverted to accounts of the unnamed Saudi-based group.

Earlier this week, AT&T said it was investigating an attempt to access customer information, but did not believe any accounts had been breached.

The CIDG said the FBI sought the help of its Anti-Transnational and Cyber Crime Division (ATCCD) in March after they found the Saudi group had targeted AT&T using the hackers.

Among the four arrested was 29-year-old Paul Michael Kwan, who ATCCD chief Police Senior Superintendent Gilbert Sosa said had been arrested in 2007 after the FBI launched an international crackdown on groups suspected of financing militant activities.

Sosa said in the statement the Filipinos were being paid by a group originally run by Muhammad Zamir, a Pakistani arrested in Italy in 2007. He said Zamir was a member of Jemaah Islamiah, a Southeast Asian militant network with links to al Qaeda.

"Zamir's group, later tagged by the FBI to be the financial source of the terrorist attack in Mumbai, India, on November 26, 2008, is also the same group that paid Kwan's group of hackers in Manila," Sosa said in the statement.

Last month, Philippine police said weak laws against cyber crime and poor technical capabilities had made the country an attractive base for organized crime syndicates involved in cyber pornography, cyber sex dens, illegal gambling, credit card fraud and identity theft.

(Reporting by John Mair in Manila and Jim Finkle in Boston; Editing by Nick Macfie)

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/nm/20111126/wl_nm/us_philippines_usa

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Courteney Cox Would Consider Being A Real-Life ?Cougar?

Courteney Cox Would Consider Being A Real-Life “Cougar”

Actress Courteney Cox doesn’t really consider herself a “cougar”, but admits she has always been attracted to younger guys like her “Cougar Town” character, Jules [...]

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Thousands rally in Egypt on "last chance Friday" (Reuters)

CAIRO (Reuters) ? Tens of thousands of Egyptians demanding an end to military rule converged on Cairo's Tahrir square on Friday in what activists say will be the biggest day yet in a week of demonstrations in which 41 people have been killed.

The military men who took over after people power toppled President Hosni Mubarak on February 11 are themselves under fire from protesters who accuse them of clinging to power, leading to street battles that look like a replay of February's unrest.

The ruling army council named Kamal Ganzouri, 78, who served as prime minister under Mubarak from 1996 to 1999, to head a national salvation government. Prime Minister Essam Sharaf's cabinet had resigned this week amid the protests.

The United States, long a bedrock supporter of Egypt's military, called on the generals to step aside "as soon as possible" and give real power to the new cabinet "immediately."

The military rulers say they are working on a transition of power, including parliamentary elections set for Monday, which could be overshadowed if violence continues. Some protesters say the army cannot be trusted to hold a clean vote.

Speaking to Reuters by telephone shortly after his appointment was announced, Ganzouri declined to reveal details of his new cabinet.

"Everything will be outlined later," he said.

After his appointment was confirmed, crowds in Tahrir chanted: "They brought a thief and appointed another thief," referring to Sharaf and Ganzouri.

"Say without fear: the (army) council must leave," they shouted.

Activists sought to bring a million people into the streets of Cairo on what they dubbed "the Friday of the last chance."

Thousands flooded into Tahrir Square for prayers, where Sheikh Mazhar Shahin told worshippers the protest would go on until Egypt had a new salvation government.

Protesters said they expected the crowd to continue to grow in the afternoon. Friday, the weekly Muslim prayer day, has traditionally been the biggest day of demonstrations in the "Arab Spring" protests sweeping the Middle East this year.

"We are all for the revolution and stand steadfast for the demands of the revolution. There is no conflict between us and the army," the cleric said in an address over loudspeakers.

BATTLE ZONES

Until a truce calmed violence on Thursday, streets around Tahrir had become battle zones with stone-throwing protesters fought police firing tear gas, pellets and rubber bullets.

A steady stream of men, women and children surged into Tahrir before Friday prayers. Some, like Atef Sayed, 45, with his wife and two daughters, were protesting for the first time.

"We're here to back the idea that the military council hands responsibility to civilians and focuses on military affairs. Nine months have gone by with many things that have happened in a way opposite to what the revolutionaries wanted," he said.

But enthusiasm for the protests was not universal.

About 5,000 people waving Egyptian flags demonstrated in favor of the military rulers in Cairo's Abbassiya district.

"The people want the emptying of the square," shouted the demonstrators. A big banner read: "Egypt will not be governed from Tahrir square."

Activists who tried to organize a march to Tahrir from a mosque in the capital's Shubra neighborhood were rebuffed.

"The army council will leave in six months. We have elections in three days. What do these people want?" asked one worshipper angrily. "They are hired to start trouble."

The White House stepped up pressure on Egypt's military rulers to speed up the handover to civilian control.

"Full transfer of power to a civilian government must take place in a just and inclusive manner that responds to the legitimate aspirations of the Egyptian people, as soon as possible," White House spokesman Jay Carney said in a statement.

"The United States strongly believes that the new Egyptian government must be empowered with real authority immediately."

Activists set up checkpoints at entrances to Tahrir square, searching people arriving and checking identity cards.

"We've had enough of government controlled by the military," read a huge banner tied between two lamp posts. Several hundred young men marched around waving Egyptian flags and chanting "Down, down with military rule" and "Down, down with the field marshal," a reference to army chief Mohamed Hussein Tantawi.

FRUSTRATION WITH ARMY

The army, once hailed for its role in easing Mubarak from power, has come under increasing fire for dragging out a handover to civilian rule, even as Egypt's economy falters.

This week it promised to accelerate the timetable for a transfer of power to a civilian president and again pledged that parliamentary elections will start on Monday as planned.

The army and the Muslim Brotherhood, which expects to do well in the election, say it must go ahead, but many protesters do not trust the military to oversee a clean vote. Some scorn the Brotherhood for its focus on gaining seats in parliament.

The group organised a protest last Friday against army efforts to shape a new constitution, but left Tahrir as protests widened. It held a separate rally this Friday at al-Azhar mosque for the "liberation" of Jerusalem from Israeli control.

The Health Ministry said 41 people have died in the week's violence, state television reported. More than 2,000 people were also wounded in the unrest in Cairo and several other cities.

The latest upheaval makes it even harder to dig the economy out of a crisis whose first victims are the millions of poor Egyptians whose frustration spurred the revolt against Mubarak.

Egypt's central bank unexpectedly raised interest rates on Thursday for the first time in more than two years, after depleting its foreign reserves trying to defend a local currency weakened by the political chaos.

In fresh blows to confidence, the Egyptian pound weakened to more than six to the dollar for the first time since January 2005, and Standard & Poor's cut Egypt's credit rating.

The economic woes may argue in favor of Ganzouri, whose government virtually balanced the budget, cut inflation, held the exchange rate stable and maintained healthy foreign currency reserves during his time in office from 1996 to 1999.

He introduced some economic liberalisation measures and many Egyptians viewed him as an official who was not tainted by corruption. But his record serving under Mubarak could stir opposition from those demanding a clean break with the past.

Some Facebook activists derided the choice of a Mubarak-era man to steer the country into a new era, listing four ancient pharaohs as useful alternatives if Ganzouri turns the job down.

"Tutankhamun is more suitable because he is from the youth," one said, referring to the boy king of ancient Egypt.

(Additional reporting by Shaimaa Fayed, Edmund Blair, Ali Abd El-Ati, Patrick Werr and Tamim Elyan; Writing by Alistair Lyon; Editing by Peter Graff)

Source: http://us.rd.yahoo.com/dailynews/rss/africa/*http%3A//news.yahoo.com/s/nm/20111125/wl_nm/us_egypt_protests

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Stocks on track for 6th day of losses on Europe fears (Reuters)

NEW YORK (Reuters) ? Stocks tumbled about 2 percent and were on track for a sixth straight day of losses on Wednesday as frustration over the euro zone debt crisis coupled with weak Chinese factory data sank sentiment.

A weak German bond sale sparked fears the debt crisis was even beginning to threaten Berlin, with the leaders of France and Germany still at odds over a longer-term structural solution.

The poor demand for German government bonds showed that investors viewed investing in the euro zone as being too risky.

Debt problems plaguing Europe and the United States have pressured markets, knocking the S&P down more than 7 percent over the last six sessions. World stocks hit their lowest in six weeks on Wednesday.

"As the selling across German bunds deepens with investors questioning the safety of its debt, investors are slowly realizing that yields may lurch higher across the spectrum, creating yet another leg lower for sentiment. Such a negative feedback loop was hardly in the cards," said Andrew Wilkinson, chief economic strategist at Miller Tabak & Co in New York.

The Dow Jones industrial average (.DJI) slid 201.88 points, or 1.76 percent, at 11,291.84. The Standard & Poor's 500 Index (.SPX) dropped 21.86 points, or 1.84 percent, at 1,166.18. The Nasdaq Composite Index (.IXIC) took off 51.82 points, or 2.06 percent, at 2,469.46.

All 10 S&P sectors were negative, with financials among the biggest decliners over concerns about exposure to European debt. JPMorgan Chase & Co (JPM.N) dropped 3 percent to $28.52 and Citigroup Inc (C.N) lost 3.6 percent to $23.60.

Economically sensitive stocks such as energy and commodity-related issues were also lower. The PHLX oil service sector index (.OSX) dropped 3.4 percent and the S&P materials sector (.GSPM) fell 2.3 percent. Schlumberger Ltd (SLB.N) was down 3.3 percent to $66.66 and DuPont and Co (DD.N) was off 2.6 percent to $44.24.

Volume was light ahead of the U.S. Thanksgiving holiday, when markets are closed.

One of the few bright spots, Deere & Co (DE.N) climbed 3 percent to $74.05 after quarterly earnings beat expectations and sales climbed 20 percent.

Adding to market worries, data showed Chinese manufacturing shrank the most in 32 months in November, intensifying concerns about a global economic slowdown. U.S. crude oil fell 1.8 percent on fears of reduced demand from China, the world's No. 2 economy.

U.S. data painted a mixed picture and showed little reason for optimism. New jobless claims rose last week and consumer spending barely increased in October, while another report showed new orders for a range of long-lasting manufactured goods rose.

(Reporting by Angela Moon; editing by Jeffrey Benkoe)

Source: http://us.rd.yahoo.com/dailynews/rss/business/*http%3A//news.yahoo.com/s/nm/20111123/bs_nm/us_markets_stocks

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Iran minister says sanctions a "lose-lose game" (Reuters)

TEHRAN (Reuters) ? Iran's trade minister said Monday sanctions were hitting the economy but warned Western countries threatening to tighten the measures that they were harming their own interests.

In a change of tone from Tehran's usual line that sanctions have not damaged the economy, Minister of Industry, Mine and Commerce Mehdi Ghazanfari said the West was losing out too.

"Sanctions are a lose-lose game in which both side make a loss. If they don't invest in our oil projects, they will lose an appealing market," Ghazanfari told a news conference.

The comments came ahead of an expected announcement by the U.S. Treasury Department later Monday designating Iran an area of "primary money laundering concern" a move allowing it to take steps to further isolate Iran's financial sector.

President Mahmoud Ahmadinejad has often said sanctions are having little effect on the economy and in some cases have made it stronger by making Iran find domestic solutions to economic challenges.

Ghazanfari reiterated the stance that Iran had found alternatives to Western imports and investments, but did not deny the downside.

"Facing hardship in a fight is inevitable. I admit projects will get harder as our trading costs will go up, delays will hit projects and money transfer will get harder," he said.

"There is a difference between hardship and the impossible. (Sanctions) will never make the running of the country impossible. There are dozens of possible ways for us to connect to the world and we are not yet using all of them."

The U.N. Security Council has imposed four rounds of sanctions on Iran since 2006 but Russia and China oppose any further ones, leaving the United States to issue unilateral measures and pressure its allies to follow suit.

After the U.N.'s atomic agency said last week the Islamic state appeared to have worked on designing an atom bomb, Washington has lined up new sanctions on Iran's petrochemical industry, sources have told Reuters.

Ghazanfari said several Western countries remained major trading partners for Iran, citing Germany, Switzerland, France, Italy among the top ten countries exporting to Iran.

(Writing by Ramin Mostafavi; Editing by Rosalind Russell)

Source: http://us.rd.yahoo.com/dailynews/rss/religion/*http%3A//news.yahoo.com/s/nm/20111121/wl_nm/us_iran_sanctions_minister

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Tascam iM2: Hi-Fi Stereo Mic for iPhone, iPad

I wish I’d found out about this stereo iPhone mic yesterday. I was last-minute shopping for dictaphone for the Lady’s work, trying to find the cheapest MP3-recording model that wouldn’t suck. It was fine, but cost nearly $90. That’s $90 that could have been spent on this iM2 Stereo Microphone from Tascam, with money to [...]

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Siri Hacked to Control a Thermostat ? What?s Next?

The release of a Siri-hacking instruction manual has made it possible for developers to push the limits of Apple's voice-controlled digital assistant. Most recently, Apple's technology was modded to control a thermostat. But Siri -- and voice control in general -- could soon be used to take over our entire home experience.

Source: http://feedproxy.google.com/~r/GearFactor/~3/-cdI2_zQZy4/

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3 missing Boy Scouts found safe in NC mountains (Providence Journal)

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Suu Kyi to run for Myanmar parliamentary seat (Reuters)

YANGON (Reuters) ? Myanmar democracy leader Aung San Suu Kyi will run in a parliamentary by-election expected by the end of the year, a top party official said on Monday, giving legitimacy to moves toward democracy after decades of military rule.

It will be the first time the Nobel Peace Prize laureate contests a seat herself, having not stood as a candidate in her National League for Democracy's (NLD) 1990 election landslide, which was ignored by the then military regime and led to her lengthy incarceration.

"Aung San Suu Kyi intends to stand for the by-election but it's a bit early to say from which constituency she will run," Nyan Win, a member of the NLD's executive committee, told Reuters.

There are 48 seats available in Myanmar's new senate and lower house.

The NLD was officially dissolved by the military junta for refusing to take part in last year's parliamentary polls because of "unfair and unjust" laws that would have prevented hundreds of its members from becoming lawmakers.

But the party voted unanimously on Friday to re-enter the political fray following an amendment to the constitution allowing those who have served sentences for crimes to take part in elections. Many NLD members, including Suu Kyi, are current or former political prisoners.

Suu Kyi is the daughter of late independence hero Aung San and was a staunch opponent of the military during its 49 years of totalitarian rule. However, she has shown willingness to meet with the new civilian government, even though it is run by former junta generals.

Aung Naing Oo, a Myanmar expert with the Thailand-based Vahu development institute, said her decision to take part in the much-criticized political system would mark the beginning of an "irreversible democratic transition."

"Aung San Suu Kyi has realized that she needs to work with the government to move the country forward and she'll be in a position to say and do a lot more. She'll bring a lot of things to the game," he said.

"She can make a big difference. Even if we have only a little bit of democracy, something here is happening that no one has seen before. For the country to change, this needed to happen."

Since the annulled 1990 polls, Suu Kyi, 66, has spent most of the time in detention. She was released a year ago and still chooses to live in the lakeside house that was her prison on and off for 15 years.

U.S. ENDORSEMENT

She had earlier given no indication she was interested in becoming a lawmaker but has always referred to herself as a politician.

Her decision comes after Myanmar won a powerful endorsement on Friday, with U.S. President Barack Obama announcing Secretary of State Hillary Clinton would visit the resource-rich country neighboring China next month, citing "flickers of progress."

For sanctions to be eased, Clinton has said the release of more political prisoners and a peace deal with ethnic minorities would be necessary. Suu Kyi and the NLD would be expected to pursue these issues aggressively in parliament.

The legislature convened in February and is Myanmar's first since the late 1980s, when a unicameral "People's Assembly" controlled by the military's Burma Socialist Program Party was scrapped.

Myanmar has so far released about 280 political prisoners this year and another amnesty is expected in the coming months.

The NLD, Myanmar's biggest opposition force, would have dominated parliament had the 1990 result been accepted by the junta. The regime annulled the 1990 result only last year, arguing that the NLD's win could not be recognized because it was in breach of a constitution drafted 18 years later.

Suu Kyi commands considerable influence over the party and Ko Ko Hlaing, a senior adviser to President Thein Sein, said on the sidelines of a regional summit in Bali last week that the NLD's decision to re-register was a "significant step."

The presence of Suu Kyi in a parliament that was criticized initially as a rubber stamp with limited scope for debate would be another dramatic sign of the openness that could give more legitimacy to the retired generals in control of the country, who are seeking acceptance, engagement, support and investment from the international community.

The NLD's Nyan Win said the party would change its structure and would prioritize younger members and those from Myanmar's multitude of ethnic groups when choosing candidates for the by-elections.

(Writing by Jason Szep and Martin Petty; Editing by Paul Tait)

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/nm/20111121/wl_nm/us_myanmar_suukyi

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Open Thread (Balloon Juice)

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MF Global trustee says $1.2B or more missing

WASHINGTON (AP) ? The court-appointed trustee overseeing MF Global's bankruptcy says up to $1.2 billion is missing from customer accounts, double what the firm had reported to regulators last month.

The trustee, James Giddens, also said in a statement Monday that his plans to release about $520 million from accounts that have been frozen will mean nearly all the assets under his control will be distributed.

Giddens has been combing through the accounts and finances of MF Global, which filed for bankruptcy protection on Oct. 31.

Regulators are investigating whether MF Global tapped money from clients' accounts as its own financial condition worsened. That would be a violation of securities rules. The FBI is investigating whether New York-based MF Global violated any criminal laws.

MF Global was led by former New Jersey Gov. Jon Corzine. The firm collapsed after making a disastrous bet on European debt.

Giddens's office said in a statement that "the apparent shortfall" was as much as $1.2 billion or more, but noted that the figure could change.

Last week, the judge overseeing the bankruptcy proceeding approved Giddens's request that 60 percent of the funds in about 23,300 frozen cash-only accounts be returned to customers. The money could start moving to customers before Thanksgiving, a spokesman for Giddens said.

Giddens has previously returned to customers $1.5 billion in collateral for their trading accounts with MF Global. He has a goal of eventually returning 100 percent of all funds to customers, though that could be reduced by the apparent shortfall.

Customers use the accounts for trading derivatives. The value of derivatives is based on the value of an underlying asset, such as interest rates, oil prices or currency rates. MF Global was one of the biggest players in the derivatives market.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2011-11-21-MF%20Global/id-c0899c386ba2460c9ae73853a85cbc57

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Troops Crack Down in Syria, Egypt

Bashar Assad soldiers targeted by army defectors

(NEWSER) - More than 70 Syrians died in a single day yesterday, many of them soldiers killed at the hands of army defectors in Daraa, activists tell the AP . The bloody wave was also felt in Homs, where the morgue had taken in 19 bullet-riddled corpses. Witnesses on the ground in Daraa reported four hours of heavy gunfire and at least 12 civilian deaths, while a British group said it had counted 34 dead soldiers. "I saw two army armored personnel carriers, totally burnt," says one witness. More?

Source: http://www.newser.com/story/133701/troops-attack-protesters-in-syria-egypt.html

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Star-studded sendoff for Heavy D (AP)

MOUNT VERNON, N.Y. ? Heavy D was remembered with laughter and tears Friday during a star-studded funeral service that included Jay-Z and Will Smith, humorous anecdotes from longtime friend Diddy, and words of encouragement for his young daughter, delivered in a letter from President Barack Obama.

"We extend our heartfelt condolences at this difficult time. He will be remembered for his infectious optimism and many contributions to American music. Please know that you and your family will be in our thoughts and prayers," read the Obama note, according to the Rev. Al Sharpton, who quoted from it during the service.

Xea Myers, Heavy D's 11-year-old daughter, also spoke briefly, telling the audience that her father was "still here, not in the flesh, but in the spirit."

Grace Baptist Church was filled to capacity for the two-and-half-hour service, which was also streamed live on the Web. It was so crowded, an overflow area was set up. Among those in attendance were Usher, Queen Latifah, Don King, Q-Tip, John Legend and Rosie Perez.

A large photo of Heavy D sat next to his closed casket.

Heavy D died last week in Los Angeles at the age of 44. His family said the death was due to complications from pneumonia.

The self-proclaimed "Overweight Lover" was born in Jamaica but reared in Mount Vernon, which he dubbed "Money Earnin' Mount Vernon." It was also the home of Sean "Diddy" Combs. Diddy talked about how Heavy D helped give him his start in the music industry, and how their decades-long friendship continued up until Heavy D's death.

"He became my friend. He became my brother. And I'm not talking about friend-brother like we cavalierly use the word, I'm talking about a real friend, a real brother," Diddy said. "Somebody I shared my dreams and my secrets with, somebody that's been for me at my lowest point, my darkest hour when nobody wanted to be beside me."

But he also told jokes as he recounted his "bromance" with the rapper, including a recent visit to Miami that was supposed to last for three days, but "turned into three weeks." He added that Heavy D got to know his chef "very well."

Sharpton also drew laughter when he noted that James Brown "us black and proud; he (Heavy D) made us fat and proud."

But singer Johnny Gill was tearful when he approached the altar, saying: "Just want to say to Heavy: job well done." He later gave a powerful rendition the gospel hit "Never Would Have Made It." The rappers nieces were also teary-eyed as they sang the gospel standard "His Eye on the Sparrow."

Heavy D, whose real name was Dwight Myers, was influential in the development of rap as it grew into a phenomenon in the late 1980s and 1990s. His hits included "Now That We've Found Love" and "Nuttin' But Love"; much of his music marked the "New Jack Swing" era in urban music, and he stood out from the pack with his rhymes, typified by a positive vibe and a lightheartedness that endeared him to so many.

A fund has been set up to financially aid Heavy D's daughter; details were available on the website rememberheavyd.com.

Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20111118/ap_on_en_mu/us_heavy_d_funeral

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Video: Juror reactions to Foley case

Dateline NBC

'Dateline NBC,' the signature broadcast for NBC News in primetime, premiered in 1992. Since then, it has been pioneering a new approach to primetime news programming. The multi-night franchise, supplemented by frequent specials, allows NBC to consistently and comprehensively present the highest-quality reporting, investigative features, breaking news coverage and newsmaker profiles.

Source: http://www.msnbc.msn.com/id/3032600/vp/45363034#45363034

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Obama and Wen Jiabao of China Talk at Asian Meeting

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Source: www.nytimes.com --- Saturday, November 19, 2011
Prime Minister Wen Jiabao of China and President Obama met unexpectedly after a week in which the United States sought to make clear that it was re-engaging in Asia. ...

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PC Hardware Makers Pulling Back On Tablet Manufacturing

Digitimes, quoting "sources from upstream supply chains," is stating that PC manufacturers like Dell, Acer, and HP are building fewer tablet products in direct reaction to devices like the iPad, Kindle Fire, and Nook Tablet. Citing an inability to gain traction against devices with rich content to back them up, the manufacturers are looking elsewhere to regain a foothold in the mobile market. In truth, manufacturers know they won't get far building vehicles for Android, Google Music notwithstanding. Building and marketing a tablet like the Xoom or the Asus Transformer is a perilous process and is buffeted by the whims of a price-conscious consumer. It doesn't make economic sense to build and try to sell a few hundred thousand slates that will be considered obsolete in a few months.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/pQAIzvz6g_4/

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Column: Blame Blatter? Blame soccer, too

/

By JOHN LEICESTER

updated 4:13 p.m. ET Nov. 17, 2011

"Resign!" howled Sepp Blatter's critics in England after the FIFA boss spouted ill-timed and offensive views on racism in soccer.

Easy. Too easy.

It's the sort of thing many people would agree with. But simply saying something is unpleasant doesn't make it go away.

That takes action. And, in that regard, soccer has failed. Miserably.

It is soccer's own fault that Blatter is still in charge, still able to dismay and infuriate from FIFA's glass fortress in Switzerland.

Those who run the global game, the soccer federation officials around the world who, ultimately, are Blatter's electorate, have had umpteen reasons to ditch him or call for his head before this latest episode. But they've stuck by him.

So they shoulder responsibility for giving a platform to his views, too. Remember: FIFA member countries awarded Blatter a fourth four-year term just five months ago despite bribery allegations, ugly internal politicking and match-fixing and corruption cases in the sport that have shredded the credibility of soccer's governing body and the men who lead it.

Not only did the fawning FIFA congress allow Blatter to stand unopposed, it gave him 91 percent of the vote. The regime in North Korea couldn't have done much better. There are no courageous rebels leading an Arab Spring uprising in soccer and none on the horizon, either.

Why?

One reason is money.

Under Blatter, FIFA has raked in mounds of the stuff. It has built financial reserves of more than $1 billion. It has the cash-cow World Cup. It sits atop a giant of a sport that is still growing in popularity, especially in promising markets in Asia and the Middle East.

One of Blatter's tricks during his nearly 14 years as FIFA president has been to ensure that gravy is spread around. Tens of millions of dollars in soccer development money doled out here, special $550,000 bonuses for all FIFA member associations in 2010 there. Seats on FIFA committees for the favored.

The former amateur soccer player is also a proven master of keeping friends and enemies close. It is a testimony to Blatter's power, to his people and management skills, and to inertia and acceptance within soccer that even at the end of this year of atrocious headlines for FIFA, there appears to be so little appetite at the top of the sport to question Blatter's leadership or methods.

Clearly, judging from his subsequent efforts to extract both feet from his mouth, Blatter realized that he wasn't clever to say this week in television interviews that racism isn't an issue on soccer fields. Even worse, he suggested that players who are victims of racist slurs should simply shake hands with and forgive their abusers at the end of a match.

That Blatter could blithely voice such absurdities when police and soccer officials in England are investigating two cases of on-field alleged racist abuse between players in the Premier League made the FIFA president look willfully insensitive and hopelessly out of touch.

When Blatter later backtracked with a statement acknowledging that "racism unfortunately continues to exist in football," FIFA's website published it with a 2009 photo of him embracing Tokyo Sexwale, a South African government minister and former Robben Island prisoner. How clumsy. All that was missing was a caption reading, "Look, Blatter likes black people and they like him!"

But where was the subsequent outpouring of shock and anger from the global game? Didn't happen. Soccer federations around the world were hardly lining up to distance themselves from Blatter. Aside from Britain, where Sports Minister Hugh Robertson declared, "For the sake of the game, he should go," the FIFA president's comments didn't seem to cause much of a ripple from soccer authorities. Many said nothing.

Blatter hasn't seen a need to step aside over any of the numerous corruption allegations that have undermined faith in FIFA and his leadership.

He didn't see fit to slink off for calling on female soccer players to wear "tighter shorts" in 2004 or for making light of the strict laws against homosexuality in Qatar, the 2022 World Cup host.

He's not going to resign now.

Of course, the great global game of soccer should have a forward-looking, scrupulously honest, modern, transparent, humble, open and intelligent leader.

It has Blatter. Who's fault is that? The easy route is to say he should go. The more constructive one would be if those with power in soccer actually did something about it.

___

John Leicester is an international sports columnist for The Associated Press. Write to him at jleicester(at)ap.org or follow him at twitter.com/johnleicester

Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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More newsHarold Cunningham / Getty Images

Blatter faces calls to resign

??With his organization still reeling from corruption allegations, FIFA President Sepp Blatter faced calls for his resignation Thursday after saying racial abuse on the soccer field could be settled by a handshake and quickly forgotten.

Eitan Abramovich / AFP - Getty Images

Source: http://nbcsports.msnbc.com/id/45344822/ns/sports-soccer/

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NBA Stars Host ?Obama Classic? to Raise Cash for 2012 (ABC News)

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